Suspect screening analysis in house dust from Belgium using high resolution mass spectrometry; prioritization list and newly identified chemicals

In recent years, several changes have been made to the composition of various products which are used indoors. Plenty new chemical additives incorporated materials comply with current legislation and safety rules. Consequently, emission profiles contaminants detected indoors may change over time, requiring continuous monitoring. this study, dust samples were collected from 25 homes located in Flemish region Belgium during different seasons (winter summer). Our aim was development a suspect screening workflow for identification chemicals might applied indoor goods, released into environment, accumulated dust. An -house list curated including selected groups compounds, namely “phthalates”, “phosphates”, “terephthalates”, “citrates”, “trimellitates”, (di-, tri-, tetra-) “carboxylic acids”, “adipates”, “azelates”, “sebacates”, (di-)“benzoates”, “succinates”. 63 prioritized based on their level detection frequency samples. Seasonal comparison tested, indicating that higher temperatures summer facilitate release few environment. Seven chemicals, best our knowledge not previously reported, out listed identified structure confirmation using high-resolution mass spectrometry. Tributyl trimellitate (TBTM), bis (3,5,5-trimethylhexyl) phosphate (Bis-3,5,5-TMHPh), iso-octyl 2-phenoxy ethyl terephthalate (IOPhET), dimethyl azelate (DMA), sebacate (DMS), dipropylene glycol dibenzoate (DiPGDB) 3,5-di- tert -butyl-4-hydroxybenzaldehyde (BHT-CHO) at frequencies ranging 8 52% winter 4–56% •An i n-house generation prepared. •Suspect analysis house •Two priority lists generated. •Seasonal influence profile linked vapor pressure values. •Seven compounds